Which antibiotic is associated with myopathy and requires monitoring of creatine kinase levels?

Daptomycin is an antibiotic that belongs to the class of lipopeptide antibiotics and is primarily used to treat infections caused by Gram-positive bacteria, including complicated skin and soft tissue infections and bacteremia. One of the notable side effects associated with daptomycin is myopathy, which is characterized by muscle weakness and pain. This condition occurs because daptomycin can lead to elevated levels of creatine kinase (CK), an enzyme that is released into the bloodstream when muscle tissue is damaged.

Due to the potential for muscle toxicity, it is crucial for healthcare providers to monitor the levels of creatine kinase in patients receiving daptomycin, especially if they're on prolonged therapy or have risk factors for muscle injury. Elevated CK levels can be an early indication of muscle damage and may necessitate adjustments in therapy or discontinuation of the drug.

In contrast, vancomycin is a glycopeptide antibiotic, clindamycin is a lincosamide antibiotic, and ciprofloxacin is a fluoroquinolone. While these antibiotics can have their own side effects and may require monitoring for various reasons, they are not primarily associated with myopathy or the need to monitor creatine kinase levels in clinical practice. Therefore, daptomy