Which drug is used topically to treat impetigo?

Mupirocin is specifically designed for topical use and is effective in treating impetigo, which is a common skin infection often seen in children. This drug works by inhibiting bacterial protein synthesis, which hinders the growth of bacteria such as Staphylococcus aureus and Streptococcus pyogenes, the most common pathogens associated with impetigo. Its formulation as a topical ointment allows for direct application to the affected area, ensuring concentrated action where needed while minimizing systemic absorption and potential side effects.

Other drugs listed may have roles in treating bacterial infections but are not typically used topically for impetigo. Clindamycin, while effective against some bacterial infections, is administered either orally or as a parenteral medication and is not the first-line treatment for impetigo. Linezolid is primarily used for more serious infections caused by resistant Gram-positive bacteria and is available in oral and intravenous forms rather than topical, making it unsuitable for localized skin infections like impetigo. Chloramphenicol is rarely used for skin infections due to potential systemic side effects and resistance issues; although it has topical formulations, it is not the preferred choice for impetigo treatment.