Which of the following best describes the primary action of cephalosporins?

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Study for the Antimicrobials Test. Prepare with flashcards and multiple choice questions, each with hints and explanations. Get ready for your exam!

Cephalosporins are a class of antibiotics that primarily act by disrupting bacterial cell wall synthesis. This mechanism is critical for their effectiveness against a wide range of both gram-positive and gram-negative bacteria. The cell wall provides structural integrity to the bacterial cell, and by inhibiting its synthesis, cephalosporins cause the cells to weaken and eventually lyse, leading to bacterial death.

The structure of cephalosporins allows them to bind to specific proteins known as penicillin-binding proteins (PBPs) located within the bacterial cell wall. These proteins play a pivotal role in the cross-linking of peptidoglycan layers, which are vital for maintaining the rigidity and shape of the bacterial cell. By preventing this cross-linking, cephalosporins weaken the cell wall and make the bacteria more susceptible to osmotic pressure, ultimately resulting in cell lysis.

In contrast, the other options refer to different mechanisms of action associated with other classes of antibiotics. Some antibiotics, for example, work by inhibiting protein synthesis or nucleic acid synthesis, but those are not the primary action of cephalosporins. Additionally, enhancing immune response is not a direct action of any antibiotic, as antibiotics primarily target the bacteria causing the

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